Darou Afshan Shaygan Pharmaceutical Company was founded by Mr. Mojtaba Shahdoost in 2016 in Tehran. Its main activities are comprised of manufacturing, importing, and exporting of pharmaceutical products, dietary supplements, and raw materials. Darou Afshan Shaygan Pharmaceutical Company has successfully managed to play a positive role in maintaining and improving the overall health of the general population by producing health-related products in various pharmaceutical forms (tablets, capsules, pellets, syrups, suspensions, and drops) using new and upgraded formulations. Darou Afshan Shaygan Pharmaceutical Company is fully determined to continue its path to provide high-quality products, exceptional service, and world-class support in order to promote overall national health and improve the quality of life both domestically and internationally.
With a motto of “Eternal Health”, Darou Afshan Shaygan Pharmaceutical Company firmly believes that health should be considered as the greatest gift of God. Moreover, with a strong and unwavering commitment to the company’s policy and guidelines, this company has full confidence in achieving the core concept of this motto. Thus, achieving lasting and eternal health is the mission of Darou Afshan Shaygan Pharmaceutical Company. Accordingly, the supplied raw material and manufactured products are in compliance with GMP principles while international standards have been considered in terms of quality, safety, and effectiveness.
Furthermore, keeping in line with its motto of “Shaygan, Eternal Health”, Darou Afshan Shaygan Pharmaceutical Company strives to play a major role in promoting overall national health and with an inclusive determination, efficient teamwork, and synergy aim to maintain the interests of all its stakeholders and customers. For this very reason, Mr. Mojtaba Shahdoost, as the founder of Darou Afshan Shaygan Pharmaceutical Company, has been proudly selected and awarded as one of the best entrepreneurs in the country.
At the moment, the research and development experts at Darou Afshan Shaygan Pharmaceutical Company have proudly manufactured 15 high-quality pharmaceutical products and dietary supplements in Iran in order to show its positive and effective role in maintaining and improving the overall health of the general population. Among these products, the utilization and introduction of the active form of folate instead of folic acid (the inactive form of folate) is perhaps the most paramount. In fact, Darou Afshan Shaygan Pharmaceutical Company is the first company that has been able to provide the general population with the active form of folate in Iran. Most of the folate assumption is coming from folic acid man-made version in supplements and added to foods. Folic acid (like food folate) is inactive and needs to be metabolized to 5-methyltetrahydrofolate (5-MTHF) to become metabolically effective. Today we know that the folic acid has a complex metabolization and that people assuming folic acid may still be gravely folate-deficient because of the big variations in how efficiently folic acid is converted into the bioactive form in different people since research has shown that up to 40% of the world’s population cannot perform this conversion effectively.
The fourth generation folate is endowed with long-lasting stability as well as a peculiarly high water solubility, improved bioavailability, and well-established safety. Several studies have reported an increase in serum of unmetabolized folic acid (UMFA) levels since the implementation of folic acid fortification, with possible concern about its potential ‘overdosing’ and adverse effects. The active form of folate is unlikely to mask the vitamin B12 deficiency and its hematologic symptoms as the pathway where it is involved is vitamin B12 dependent. The level of folate and homocysteine status are critical factors in the early stages of human reproduction. Women and men experiencing fertility issues can present low folate availability, often linked to the presence of MTHFR polymorphism. Rapidly developing cells in the embryo may suffer from a lack of adequate folate. Failure to produce sufficient DNA and to regulate DNA function could lead to spontaneous abortion. Several studies have investigated maternal enzyme polymorphism in the metabolization of folate as a risk factor for Down Syndrome.
Darou Afshan Shaygan Pharmaceutical Company has specifically used the active form of folate instead of folic acid in all of its products. Among these products, one can refer to “Best Folate®” (the active form of folate instead of folic acid), “QuatreIode®” (the active form of folate with Iodine for women before and during pregnancy), “Quatrekids®” oral drops (active form of folate and other vitamins and minerals for infants and children), “Hairogen®” (the active form of folate and biotin for healthy skin, hair, and nails), “Ferrofolate®” (the active form of folate and Iron to treat various anemias), and “Inopergna®” (the active form of folate, inositol, magnesium, and zinc to help improve fertility and ovarian function in women).
Darou Afshan Shaygan Pharmaceutical Company, while benefiting from the creativity and insights of its expert staff and Mr. Mojtaba Shahdoost, is striving to create a culture of quality in Iran in the field of pharmaceuticals.